Pico Laser Treatment for Pigmented Lesions: Ib Daim Ntawv Qhia Kev Kho Mob Ua tiav rau cov kws kho mob

2026-06-18

Cov ntsiab lus
Pigmented lesions are skin conditions caused by abnormal pigment deposition resulting from congenital genetic defects, acquired environmental factors, or skin aging. Cov kab mob no tshwm sim nrog ntau yam kev kho mob tshwm sim, suav nrog freckles, lentigines, nevi, thiab café-au-lait chaw.
For practitioners and clinic owners looking to expand their aesthetic service offerings, understanding how to properly set treatment parameters when using Pico lasers for different types of pigmented lesions is essential for achieving optimal clinical outcomes while minimizing adverse effects. Phau ntawv qhia no muab cov ncauj lus kom ntxaws, cov ntaub ntawv pov thawj-raws li kev kho mob plaub hom kab mob pigmented nrog picosecond laser technology.

1. Pico Laser Technology: Mechanism of Action
Picosecond lasers are defined as lasers with output pulse widths in the picosecond range (typically 300–750 ps), also known as sub‑nanosecond lasers. Cov wavelengths muaj xws li 532nm, 730nm, 755nm, 785nm, thiab 1064nm.
Due to their extremely short pulse durations, picosecond lasers can achieve exceptionally high peak power instantaneously, generating a photoacoustic (photomechanical) effect on target chromophores. This effect pulverizes melanin particles into much smaller fragments compared to traditional Q‑switched nanosecond lasers, making them easier for macrophages and other phagocytic cells to clear, while producing a milder inflammatory response.
Cov txiaj ntsig tseem ceeb ntawm picosecond dhau Q-hloov nanosecond lasers suav nrog:

Superior clearance tus nqi rau pigmented lesions thiab tattoos
Yuav tsum muaj kev kho mob tsawg dua
Tsawg qhov pheej hmoo ntawm post-inflammatory hyperpigmentation (PIH)
Kev siv dav dua thoob Fitzpatrick hom tawv nqaij
Ntxiv cov txiaj ntsig zoo nkauj ntxiv nrog rau kev txhim kho daim tawv nqaij zoo nkauj thiab pore refinement

According to the Expert Consensus on the Clinical Application of Picosecond Lasers, picosecond lasers can be used to treat various epidermal and dermal pigmented lesions. Cov thev naus laus zis muaj txiaj ntsig zoo rau freckles, hnub ci lentigines, thiab nevus ntawm Ota; muaj txiaj ntsig zoo rau cov chaw café-au-lait thiab lentigines (txawm tias muaj qee qhov kev pheej hmoo rov tshwm sim); thiab tuaj yeem ua qhov kev xaiv kho mob rau cov xwm txheej nyuaj.

2. Treatment Parameter Selection: Core Principles
Before examining specific lesion types, practitioners should understand several foundational principles that apply across all pigmented lesion treatments:
2.1 Wavelength Xaiv los ntawm Lesion Depth

Lesion Depth	Pom zoo Wavelengths	Mechanism
Epidermal (freckles, hnub ci lentigines, café-au-lait chaw)	5 32nm,755nm	Qhov tob nkag mus rau lub hom phiaj melanin superficial
Mixed epidermal-dermal (melasma, qee qhov nevi)	755nm, 1064 nm	Moderate penetration addresses pigment at multiple depths
Dermal (nevus ntawm Ota, Hori's nevus)	755nm, 1064 nm	Qhov tob tob mus txog dermal melanocytes

2.2 Endpoint Reactions
Qhov kawg ntawm qhov chaw kho mob sib txawv los ntawm hom kab mob thiab kev kho mob:

Epidermal lesions (freckles, lentigines): me me dawb frosting (tam sim ntawd whitening)
Cov kab mob dermal (nevus ntawm Ota): Nruab nrab te uas tsis muaj cov ntaub so ntswg splatter (siab zog) lossis erythema tsis muaj petechiae (qis zog)
Melasma: Me erythema (mob siab, kev saib xyuas zoo)

2.3 Fitzpatrick Skin Type Considerations
Picosecond lasers can be used across a broader range of skin types than nanosecond lasers due to the reduced risk of hyper‑ or hypopigmentation associated with photoacoustic (vs. photothermal) effects. Txawm li cas los xij, kev txiav txim siab tshwj xeeb siv rau cov tawv nqaij ntawm cov xim (Fitzpatrick IV-VI):

Cov ntsiab lus epidermal melanin ntxiv kev pheej hmoo rau cov teeb meem pigmentary
Conservative settings (qis fluence, loj qhov chaw loj) raug pom zoo
Kuaj patching yog xav paub ntau ntxiv
Kev kho mob yuav tsum tau txuas ntxiv kom muaj kev kho kom zoo

3. Kev kho raws cai los ntawm Lesion Type
3.1 Freckles (Ephélides)
Freckles yog cov kab mob epidermal pigmentation ntau tshaj plaws uas tau ntsib hauv kev kho mob.
Kev xaiv Wavelength:

532nm feem ntau yog siv los kho freckle
755nm qhia tau hais tias muaj qhov txhab tshem tawm ntau dua thiab txaus siab tus nqi
730nm qhia pom kev xaiv zoo rau cov xim nrog kev puas tsuaj tsawg rau cov kab mob dermal-epidermal hlws ris

Pom zoo Parameter:

Ntaus / wavelength	Zog Ceev	Qhov Loj	Endpoint
755nm (daim duab)	4.07 J / cm²	2.5 hli	Kev ntxuav hniav dawb tam sim ntawd
730nm (picoway)	1.4-1.7 J/cm²	3 hli	Yooj yim frosting
532nm (picoway)	Txiav txim los ntawm hom tawv nqaij & kev nthuav qhia	Hloov pauv	Yooj yim frosting

Cov lus qhia kho mob:

Cov txiaj ntsig zoo tshaj plaws hauv Fitzpatrick III-IV nrog cov kab mob kom meej meej
Cov neeg mob uas muaj qhov txhab sib zog lossis melasma ib txhij muaj PIH siab dua
One session may achieve significant clearance; 1–3 sessions typically recommended
Lub sijhawm kho mob: 4-6 lub lis piam

3.2 Hnub Ci Lentigines (hnub nyoog Spots, Sunspots)
Hnub ci lentigines yog cov kab mob benign tshwm sim ntawm qhov chaw raug tshav ntuj, tshwj xeeb yog lub ntsej muag thiab nraub qaum ntawm tes, nce nrog hnub nyoog.
Kev xaiv Wavelength:

532nm lub hom phiaj ntawm cov xim sab nrauv zoo
755nm muab kev tshem tawm zoo heev nrog kev pheej hmoo PIH tsawg
730nm thiab 785nm kuj tseem siv tau

Pom zoo Parameter:

Ntaus / wavelength	Zog Ceev	Qhov Loj	Endpoint
532nm ua	0.6-1.4 J / cm²	3-6 hli	Yooj yim frosting
755nm ua	4.07 J / cm²	2.5-3 hli	Kev ntxuav hniav dawb tam sim ntawd

Cov lus qhia kho mob:

Ib lossis ob zaug tuaj yeem tshem tawm cov kab mob benign, tiaj tus
50% qhov txhab tshem tawm tau ua tiav tom qab ob txoj kev kho mob thoob plaws Fitzpatrick II-V
Lub sijhawm kho mob: 4-6 lub lis piam
Zoo heev prognosis nrog tsawg recurrence thaum lub hnub tiv thaiv yog khaws cia

3.3 Café-au-Lait Macules (CALMs)
Café-au-lait macules yog pigmented lesions feem ntau hu ua "coffee nrog mis nyuj" vim lawv lub teeb xim av. Lawv tshwm sim thaum yug los, feem ntau hu ua birthmarks, thiab nyob twj ywm hauv lub neej.
Epidemiology:

Tam sim no nyob rau hauv kwv yees li 5% ntawm Caucasians thiab mus txog 15% ntawm cov neeg Amelikas ntawm African qhovntsej thiaj tsis mob thaum yug los
Can be treated across Fitzpatrick skin types I–IV

Kev xaiv Wavelength:

532nm: Rau qhov sib dua, ntau qhov txhab tawv nqaij
755nm: Lwm txoj hauv kev zoo
1064nm: Rau cov kab mob sib sib zog nqus

Pom zoo Parameter:

Parameters should be based on skin type and lesion color
Endpoint: Me me dawb frosting

Cov lus qhia kho mob:

Kev ua tau zoo sib txawv; qee cov neeg mob qhia tau tias muaj kev txhim kho tseem ceeb thaum lwm tus muaj qhov rov muaj dua dua
Tej zaum yuav xav tau ntau ntu (1–6+)
Lub sijhawm kho mob: 4-8 lub lis piam
Cov neeg mob me tuaj yeem teb txawv dua li cov neeg laus

3.4 Nevus ntawm Ota (thiab Hori's Nevus / Tau txais ob sab Nevus ntawm Ota-zoo li Macules)
Nevus of Ota is a dermal melanocytic condition characterized by blue‑gray pigmentation in the distribution of the ophthalmic and maxillary branches of the trigeminal nerve. Hori's nevus (ABNOM) yog ib qho teeb meem ntawm daim tawv nqaij uas feem ntau raug kuaj pom tias yog melasma.
Kev xaiv Wavelength:

755nm yog qhov tseem ceeb rau nws cov txiaj ntsig hauv Hori's nevus
1064nm muab qhov tob tob rau dermal melanocytes
730nm kuj tseem siv tau rau dermal pigmentation

Pom zoo Parameter:

Mus cuag	Qhov Loj	Zog Ceev	Endpoint
Siab zog	2.5-3 hli	2.83–4.07 J/cm²	Nruab nrab Frost, tsis muaj ntaub so ntswg splatter
Tsawg Zog	4.5-5 hli	1.02–1.26 J/cm²	Erythema, tsis muaj petechiae

Cov lus qhia kho mob:

Lub sijhawm kho mob: 3-6 lub hlis
Feem ntau xav tau ntau qhov kev sib tham kom ua tiav kev tshem tawm
Cov neeg mob menyuam yaus (nevus ntawm Ota) feem ntau xav tau kev sib tham tsawg dua kom ua tiav kev tshem tawm dua li cov neeg laus
Picosecond alexandrite laser qhia tau hais tias siab dua ib zaug kev tshem tawm ntau dua li Q-hloov nanosecond lasers
Higher PIH risk in Hori’s nevus; extend treatment intervals accordingly
755nm picosecond laser muaj kev nyab xeeb thiab zoo rau kev kho mob nevus ntawm Ota hauv cov menyuam yaus

4. Cov lus qhia txog kev kho mob
4.1 Kev ntsuam xyuas ua ntej kev kho mob

Ntsuas Fitzpatrick hom tawv nqaij
Txheeb xyuas qhov xim xim, qhov tob, thiab ciam teb
Cov ntaub ntawv nrog cov qauv kev yees duab
Tshawb xyuas cov neeg mob keeb kwm rau cov tshuaj photosensitizing tshuaj, melasma, thiab PIH keeb kwm
Xav txog kev sim patching rau hom tawv nqaij tawv dua lossis cov lus teb tsis meej

4.2 Thaum kho

Siv qhov muag tiv thaiv rau tus neeg mob thiab tus neeg ua haujlwm
Siv dynamic txias los yog hu rau txias los tiv thaiv epidermis
Ua tib zoo soj ntsuam cov ntsiab lus kawg
Tsis txhob overlapping pulses ntau dhau
Rau cov kab mob dermal, xav txog kev siv qhov chaw loj dua kom txo cov cua sov ntawm cov kab mob

4.3 Kev Kho Mob Tom Qab

Siv cov tshuaj txias los yog soothing tam sim ntawd
Kev tiv thaiv lub hnub nruj (SPF 50+) tsawg kawg yog 4-6 lub lis piam
Tsis txhob exfoliants thiab irritating skincare khoom rau 1 lub lis piam
Teem sijhawm taug qab ntawm 4-8 lub lis piam los soj ntsuam cov lus teb
Saib xyuas PIH, tshwj xeeb tshaj yog nyob rau hauv Fitzpatrick III-VI

4.4 Tej Yam Tsis Txaus Siab thiab Kev Tswj Xyuas

Cov teebmeem tsis zoo	Kev tiv thaiv	Kev tswj hwm
Post-inflammatory hyperpigmentation (PIH)	Conservative parameters, test patching, sun avoidance	Tshuaj pleev tyrosinase inhibitors, tiv thaiv tshav ntuj, ncua sij hawm
Erythema / edema	Ua kom txias, tsim nyog fluence	Feem ntau nws tus kheej txwv; daws nyob rau hauv cov sij hawm mus rau hnub
Hypopigmentation	Zam kev kho mob hnyav heev hauv cov tawv nqaij tsaus	Tej zaum yuav ncua sij hawm los yog mus tas li; kev tiv thaiv yog qhov tseem ceeb

5. Qhov tseem ceeb Takeaways rau cov tswv tsev kho mob
5.1 Vim li cas thiaj muab Pico Laser Pigment Treatments?

Kev thov siab: Pigmented lesions yog ib qho kev txhawj xeeb tshaj plaws ntawm cov neeg mob
Cov txiaj ntsig tau zoo: Picosecond lasers muab kev tshem tawm zoo dua nrog tsawg zaus
Tsawg qhov tsis zoo tshwm sim profile: Txo PIH kev pheej hmoo piv rau nanosecond lasers
Versatility: Ib lub platform kho epidermal, dermal, thiab sib xyaw cov kab mob
Cov nyiaj tau los rov tshwm sim: Ntau qhov kev sib ntsib xav tau kom tau txais txiaj ntsig zoo

5.2 Kev txiav txim siab ntawm cov khoom siv

Xyuas kom koj lub Pico laser platform muaj ntau lub wavelengths (tsawg kawg 532nm thiab 1064nm, qhov zoo tshaj plaws nrog 755nm thiab 730nm xaiv)
Ua pov thawj FDA 510 (k) tshem tawm lossis CE kos rau cov cim qhia qhov nqaij tawv nqaij
Xav txog cov platforms uas hloov tau qhov ntau thiab tsawg thiab lub zog ntom ntom ntau haum rau ntau hom kab mob
Integrated cooling systems yog qhov tseem ceeb rau cov neeg mob kev nplij siab thiab kev nyab xeeb

5.3 Kev Siv Tus Nqi Kho Mob

Hom kab mob	Kev Sib Tham	Nqe Ntau (Ib ntu, USD)
Cov tawv nqaij	1–3	$200–400
Hnub ci lentigines	1–2	$250–500
Café-au-lait macules	3–6+ ib	$300–600
Nevus ntawm Ota / Hori's	5–10+	$400–800

Cov ntaub ntawv

Cov kws tshaj lij pom zoo rau Kev Kho Mob Daim Ntawv Thov Picosecond Lasers
Cov Lus Qhia rau Kev Ntsuas thiab Kev Kho Mob hauv Laser thiab Aesthetic Tshuaj (2024)
Cov Lus Qhia Txog Kev Kho Mob rau PicoWay® Laser System hauv Daim tawv nqaij xim
Picosecond Laser Treatment rau Tattoos thiab Benign Cutaneous Pigmented Lesions
Wavelength-dependent threshold fluences rau melanosome cuam tshuam (PubMed, 2024)
A Prospective, Split‑Face, Randomized Study Comparing Picosecond to Q‑Switched Nd:YAG Laser for Treatment of Epidermal and Dermal Pigmented Lesions in Asians

Kev faib:

Ua ntej ：Fractional CO2 Laser Tshuab: Ua tiav B2B Tus Neeg Yuav Khoom Phau Ntawv Qhia rau Chaw Kho Mob thiab Medspas hauv 2026

Lwm zaj：Rov qab mus rau npe

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